Giant cell tumour of the bone

Giant cell tumour of the bone

Age: Peak incidence 20 to 40 - Typically occurs after the fusion of the epiphysis

Location

- Commonly involves the long bones

- The most common location is the knee (abutting the articular surface) 65%

- Distal femur

- Proximal tibia

Radiograph

Expansile well circumscribed lytic lesion

Involves the epiphysis (after the closure)

Prominent trabeculation

No sclerotic border

Periosteal reaction in a minority of cases

Can be described as a "soap bubble" appearance

CT

Soft-tissue mass with foci of hypoattenuation (haemorrhage and necrosis)

Enhancement

Well defined margins.

It can have a thin rim of sclerosis ( in up to 20%)

Can have soft tissue extension

It may have a secondary aneurysmal bone cyst with fluid f...